tool compound — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T4314	EPZ020411	EPZ020411 2HCl	Histone Methyltransferase
	EPZ020411 is a specific and effective inhibitor of PRMT6 (IC50=10 nM).		Histone Methyltransferase
T40350	HPK1-IN-4	HPK1-IN-4	MAPK
	HPK1-IN-4 is an HPK1 (MAPK41) inhibitor with an IC 50 of 0.061 nM. HPK1-IN-4 is often used as a preclinical immunotherapy tool compound.		MAPK
T63788	PCLX-001		Others
	PCLX-001 is a small-molecule compound that acts as an orally active inhibitor of N-myristoyltransferase (NMT), specifically targeting NMT1 and NMT2 with IC50 values of 5 nM and 8 nM, respectively. This compound demonstra...		Others
T22180	3F8	3F 8,3F-8	GSK-3
	3F8 is a selective GSK-3β inhibitor that can be used as a new tool and potential therapeutic candidate compound for GSK3-related diseases, and can be used in the study of neurological disorders and cancer.		GSK-3
T9314	CC214-1		mTOR , Autophagy
	CC214-1 is an mTOR inhibitor with potential anticancer activity, inhibits protein translation, and induces autophagy. CC214-1 is an in vitro tool compound for exploring the biology of mTOR kinases and can be used to stud...		mTOR , Autophagy
T9361	5-bromo-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione	5-bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione	Others
	5-bromo-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione (5-bromo-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione) is a synthetic compound. It has been used as a catalyst and as a tool in enzyme kinetic studies; it has al...		Others
T64355	TDI-10229		cAMP
	TDI-10229 is a potent and orally available inhibitor of soluble adenylyl cyclase (sAC, ADCY10). TDI-10229 displays nanomolar inhibition of sAC in both biochemical and cellular assays (IC50= 195 nM). TDI-10229 exhibits mo...		cAMP
T38938	Antibacterial agent 37
	Antibacterial agent 37 is an effective antimicrobial compound. It holds potential as a valuable tool for researching bacterial infections.
T61868	Antitumor agent-66
	Antitumor agent-66 (Compound 4) is a derivative of (-)-cleistenolide, showcasing potential as a research tool for cancer diseases [1].
T30216	AV-105	AV105,AV 105
	Av-105 is the precursor of florbetapir (18F). It is a radiopharmaceutical compound scanned by pet, which can be used as a diagnostic tool for Alzheimer's disease.
T61423	Transthyretin-IN-1
	Transthyretin-IN-1 (Compound 1d) is a potent inhibitor of transthyretin (TTR) fibril formation, making it a valuable tool for investigating Alzheimer’s disease [1].
T38955	β-Lactamase-IN-4
	β-Lactamase-IN-4 (WO2013149121A1, compound 708) is a potent β-lactamase inhibitor. It serves as a valuable tool in the investigation of bacterial infections.
T69922	EPZ020411 HCl
	EPZ020411 is a potent and selective PRMT6 inhibitor tool compound. EPZ020411 shows good bioavailability following subcutaneous dosing in rats making it a suitable tool for in vivo studies. EPZ020411 suppresses RCC1 argin...
T39729	HIV Protease Substrate 1
	HIV Protease Substrate 1 is a fluorogenic compound that offers insights into the enzymatic activity of HIV protease, making it a valuable tool for studying this aspect.
T18373	N-(Amino-PEG4)-N-Biotin-PEG4-acid		Others
	N-(Amino-PEG4)-N-Biotin-PEG4-acid is a PEG-based PROTAC linker that incorporates biotin for labeling purposes. This compound serves as a versatile tool in the synthesis of PROTACs[1].		Others
T39270	2-NP-AMOZ
	2-NP-AMOZ is a 2-nitrophenyl derivative of AMOZ, which is a metabolite of the antibiotic Furaltadone. This chemical compound specifically serves as a reliable tool for protein bound AMOZ detection.
T39277	D-Hexamannuronic acid
	D-Hexamannuronic acid, an alginate oligomer, is derived from marine brown algae and a restricted group of Gram negative bacteria. This compound serves as a valuable tool for investigating pain and vascular dementia[4].
T61341	A-908292
	A-908292 is a highly potent and selective inhibitor of acetyl-CoA carboxylase 2 (ACC2), displaying an impressive IC50 of 38 nM. This compound serves as a valuable tool in the investigation of fatty acid metabolism [1].
T61592	Thalidomide-piperazine hydrochloride
	Thalidomide-piperazine hydrochloride is a chemical compound with potential applications in the research of leprosy and multiple myeloma. It serves as a valuable tool in developmental biology, facilitating significant dis...
T40966	D-Heptamannuronic acid
	D-Heptamannuronic acid, an alginate oligomer, is derived from marine brown algae and a select group of Gram-negative bacteria. This compound serves as a valuable research tool in the study of pain and vascular dementia[4...